Common Weight Loss Injections/Jabs: Ozempic and Mounjaro

• Ozempic: Contains semaglutide, which acts like a hormone (GLP-1) to make you feel less hungry.
• Mounjaro: Contains tirzepatide, which works on two hormones (GLP-1 and GIP) to control hunger and feeling full for longer which leads to weight loss.

• Ozempic: Helps you lose about 8-12% of your body weight (e.g., about 1-2 stone for a 14-stone person) over a year.
• Mounjaro: Works better for weight loss, helping you lose 15-25% of your body weight (e.g., 2-3.5 stone for a 14-stone person). Its dual hormone action makes it stronger.

• Both are injected once a week in your tummy, thigh, or arm.
• Ozempic: Doses go from 0.25 mg to 2 mg. You use the same pen multiple times, changing the needle each time.
• Mounjaro: Doses go from 2.5 mg to 15 mg. You use a new pen each time.

• Ozempic: Lowers blood sugar (A1C) by about 1.9%.
• Mounjaro: Lowers blood sugar more, by about 2-2.3%, so it’s better for diabetes control.

• Both can cause nausea, vomiting, diarrhoea, constipation, or tummy upset. Mounjaro might cause slightly more tummy issues because of its dual action.
• Both have a rare risk of serious issues like pancreas or thyroid problems (seen in animal studies).
• Some people find Mounjaro has fewer side effects, but it varies.

• Ozempic: Costs about £700-£800/month without insurance. Cheaper with NHS or private coverage for diabetes.
• Mounjaro: Costs about £800-£950/month, a bit pricier. NHS coverage is mostly for diabetes or weight loss in specific cases.
• Both are expensive if used for weight loss without coverage.

• Ozempic: Available since 2017, widely used, but sometimes hard to get due to demand for weight loss.
• Mounjaro: Newer (approved 2022), approved for weight loss in the UK, but supply can be limited.